누카가 미치요시
NUKAGA Michiyoshi
교수
전문 분야: 미생물학, 구조 생물학
주요 담당 과목
微生物学A、微生物学B、生体防御学、病原微生物学（看護学部）
연구 테마 및 키워드
薬剤耐性の分子機構
최종학력/학위
千葉大学/博士（薬学）
면허/자격
약사
소속 학회
日本薬学会、日本最近学会、アメリカ化学会
주요 성과
1. Mojica MF, Becka SA, Edwards M, Myers C, Uehara K, Uehara T, Hoshino T, Zeiser ET, Chatwin CL, Six DA, Bonomo RA, Papp-Wallace KM, Nukaga M. Burkholderia pseudomallei PenI β-lactamase and variants are potently inhibited by taniborbactam. Antimicrob Agents Chemother. 2025 Oct;69(10):e0078725. doi: 10.1128/aac.00787-25.
2. Kamo T, Kuroda K, Nimura S, Guo Y, Kondo S, Nukaga M, Hoshino T. Development of Inhibitory Compounds for Metallo-beta-lactamase through Computational Design and Crystallographic Analysis. Biochemistry. 2024 May 21;63(10):1278-1286. doi: 10.1021/acs.biochem.
3. Mojica MF, Nukaga M, Becka SA, Zeiser ET, Hoshino T, LiPuma JJ, Papp-Wallace KM. Frameshift Mutations in Genes Encoding PBP3 and PBP4 Trigger an Unusual, Extreme β-Lactam Resistance Phenotype in Burkholderia multivorans. ACS Infect Dis. 2024 Nov 8;10(11):3810-3820. doi: 10.1021/acsinfecdis.4c00330.
詳しい研究実績はこちら
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