Tomoyo Kamei

Main subjects

synthetic organic chemistry

Research Themes and Keywords

Research and development of reagents for determining absolute configuration, synthesis of natural products

Major achievements

1. T. Kamei, Y. Kimura, J. Koyanagi, K. Matsumoto, T. Hasegawa, M. Akimoto, T. Takahashi, Determination of the Absolute Configuration of the Nabumetone Metabolite 4-(6-Methoxy-2-naphthyl) butan-2-ol Using the Chiral Derivatizing Agent, 1-Fluoroindan-1-carboxylic acid. Chem. Pharm. Bull., 67(1), 75-785 (2019).
2. T. Kamei, T. Takahashi, H. Teramae, J. Koyanagi, Synthesis and Evaluation of FICA Derivatives as Chiral Derivatizing Agents. Chem. Pharm. Bull., 68(8), 818-8216 (2020).
3. K. Matsumoto, T. Hasegawa, K. Ohara, T. Kamei, J. Koyanagi, M. Akimoto, Role of human flavin-containing monooxygenase (FMO) 5 in the metabolism of nabumetone: Baeyer-Villiger oxidation in the activation of the intermediate metabolite, 3-hydroxy nabumetone, to the active metabolite, 6-methoxy-2-naphthylacetic acid in vitro. Xenobiotica, 51, 155-166 (2021).

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