Michiyoshi Nukaga

NUKAGA Michiyoshi

Biopharmaceuticals

area of expertise: Research into the structure of resistance mechanisms to antibacterial and antiviral drugs, and biological approaches

Main subjects

･Advanced Biopharmaceuticals ･Graduate School Special Lectures ･Graduate School Special Seminars

Research Themes and Keywords

Structural analysis of drug resistance factors and antibiotic target proteins

Final academic background/degree

Chiba / Doctor

licence · Qualification

pharmacist

Affiliated academic society

Pharmaceutical Society of Japan, Bacteriological Society of Japan, Crystallographic Society of Japan, American Chemical Society

Major achievements

1. Nukaga M, Yoon MJ, Taracilia MA, Hoshino T, Becka SA, Zeiser ET, Johnson JR, Papp-Wallace KM., Assessing the Potency of β-Lactamase Inhibitors with Diverse Inactivation Mechanisms against the PenA1 Carbapenemase from Burkholderia multivorans. ACS Infect Dis. Apr 9;7(4):826-837. (2021).
2. Kamo T, Kuroda K, Kondo S, Hayashi U, Fudo S, Yoneda T, Takaya A, Nukaga M, Hoshino T. Identification of the Inhibitory Compounds for Metallo-β-lactamases and Structural Analysis of the Binding Modes. Chem Pharm Bull (Tokyo). 69(12):1179-1183. (2021)
3. Probing the Mechanism of Inactivation of the FOX-4 Cephamycinase by Avibactam., Nukaga M, Papp-Wallace KM, Hoshino T, Lefurgy ST, Bethel CR, Barnes MD, Zeiser ET, Johnson JK, Bonomo RA., Antimicrob Agents Chemother . 62(5):e02371-17. (2018)

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