Kimihito Tashima

Main subjects

Advanced Pharmaceutical Sciences, Graduate School Special Lecture

Research theme/keyword

・Study on development of functional dyspepsia disease model animals and elucidation of therapeutic targets ・Study on temperature-sensitive channel TRPA1 and gastrointestinal function regulation

Final academic background/degree

Kyoto Pharmaceutical University / Ph.D.

licence · Qualification

Pharmacist, Pharmacology Educator

Affiliated academic society

The Japanese Ulcer Society, The Japanese Pharmacological Society, The Pharmaceutical Society of Japan, The Japanese Society of Chinese Medicine, The Japanese Society of Neurogastroenterology, The American Society of Gastroenterology

Major achievements

1. Ohashi N, Tashima K, Namiki T, Horie S. Allyl isothiocyanate, an activator of TRPA1, increases gastric mucosal blood flow through calcitonin gene-related peptide and adrenomedullin in anesthetized rats. J Pharmacol Sci. 2023 Apr;151(4) :187-194. doi: 10.1016/j.jphs.2023.02.002. Epub 2023 Feb 21. PMID: 36925217.
2. Yoshikubo M, Tashima K, Raimura M, Watanabe Y, Noma Y, Horie S. Daikenchuto, a Traditional Kampo Medicine, Facilitates Mucosal Hyperemic Responses through Activation of TRPA1- and TRPV1-Expressing Sensory Nerves in Rat Stomach. Planta Medica International Open 9(01) e72-e79, 2022
3. Hashimoto K, Tashima K, Imai T, Matsumoto K, Horie S. The rodent model of gastric motility induced impaired by allyl isothiocyanate, a pungent ingredient of wasabi, to evaluate therapeutic agents for functional dyspepsia. J Pharmacol Sci. 2021 Jan; 145(1):122-129. doi: 10.1016/j.jphs.2020.10.006. Epub 2020 Nov 11. PMID: 33357770.

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