Masami Koshi

Main subjects

Anatomical Physiology, Clinical Chemistry, Gender Life Stage Pharmacy Special Seminar, Basic Pharmacy Practicum, Biology Practicum

Research theme/keyword

Cell death control mechanism via mitochondria

Final academic background/degree

Tokyo Medical and Dental University / Doctor

licence · Qualification

clinical laboratory technician

Major achievements

1. M. Koushi, R. Asakai, Bisindolylpyrrole induces a Cpr3- and Porin 1/2-dependent transtion in yeast mitochondrial permeability in a low conductance state via the AACs-associated pore. Int. J. Mol. Sci. 22, 1212 (2021).
2. M. Koushi, Y. Aoyama, Y. Kamei, R. Asakai, Bisindolylpyrrole triggers transient mitochondrial permeability transitions to cause apoptosis in a VDAC 1/2 and cycliphilin D-dependent manner via the ANT-associated pore. Sci. Rep. 10, 16751 (2020).
3. Y. Kamei, M. Koushi, Y. Aoyama, R. Asakai, The yeast mitochondrial permeability transition is regulated by reactive oxygen species, endogenous Ca2+ and Cpr3, mediating cell death. Biochim. Biophys. Res. Commun. 1859, 1313 -1326 (2018).

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