亀井 智代
KAMEI Tomoyo
准教授
専門分野：有機合成化学
主な担当科目
有機合成化学
研究テーマ・キーワード
絶対配置決定試薬の研究開発、天然物合成
主要業績
1. T. Kamei, Y. Kimura, J. Koyanagi , K. Matsumoto, T. Hasegawa, M. Akimoto, T. Takahashi, Determination of the Absolute Configuration of the Nabumetone Metabolite 4-(6-Methoxy-2-naphthyl)butan-2-ol Using the Chiral Derivatizing Agent, 1-Fluoroindan-1-carboxylic acid. Chem. Pharm. Bull., 67(1), 75-785 (2019).
2. T. Kamei, T. Takahashi, H. Teramae, J. Koyanagi, Synthesis and Evaluation of FICA Derivatives as Chiral Derivatizing Agents. Chem. Pharm. Bull., 68(8), 818-8216 (2020).
3. K. Matsumoto, T. Hasegawa, K. Ohara, T. Kamei, J. Koyanagi, M. Akimoto, Role of human flavin-containing monooxygenase (FMO) 5 in the metabolism of nabumetone: Baeyer-Villiger oxidation in the activation of the intermediate metabolite, 3-hydroxy nabumetone, to the active metabolite, 6-methoxy-2-naphthylacetic acid in vitro. Xenobiotica, 51, 155-166 (2021).
詳しい研究実績はこちら